Survivalist Forum banner

1 - 3 of 3 Posts

·
The Power of III
Joined
·
1,365 Posts
Discussion Starter · #1 ·
Link:
http://www.recombinomics.com/News/12100904/D225G_D225N_Utah_Fatal.html

Excerpt:

he above report matches the demographic data for a case (28F) from Utah, which has D225G and D225N. The sample collection date also matches the date of death. The initial sequences were released at GISAID, but now the sequences are also available at GenBank. One sequence, A/Utah/42/2009 is from the original sample and has mixed signals for D225G and D225N. This combination could also code for D225S, although no such sequence has been described previously in pandemic H1N1. The second sequence is a clone which gives a clean D225G signal. The presence of sequences which can encode for D225G and D225N has not been reported previously in a single sample, but recently released CDC sequences from two patients in Ukraine had D225N, while four sequences from fatal cases released by Mill Hill had D225G. Both of the changes had been previously found in fatal cases in Sao Paulo Brazil and the recent association of these sequences with fatal or sever cases has raised concerns that the frequency of these changes is increasing, which could lead to more fatalities and severe cases in the next pandemic wave. . . .
more at link above
 
  • Like
Reactions: Halkon

·
Registered
Joined
·
142 Posts
It seems the mutation has been amongst us for some time since this is reported from a July case and either doesn't spread easily from the host or .......???? It seems this would have occurred prior to the Ukraine outbreak which has killed an estimated 70 people (about .02% of the infected). I'm sure more info will be gleaned as time goes on.
 

·
Registered
Joined
·
39 Posts
D225G was in a sample from April 2009 in California, and was included in a list of "targets" for the H1N1 vaccine.

It has also been found in samples from the 1918 Spanish Flu.

D225G is a change in the virus that allows it to infect deeper in the lungs and cause much more severe illness. It has been linked to fatal cases in China, Brazil, Ukraine, Norway, France and the U.S. (perhaps others as well).

D225G has also been associated with antigenetic changes that may cause it to evade immunity from prior H1N1 infection and the vaccine.

No, it's not new, but selection forces may cause it to become more widespread.
 
1 - 3 of 3 Posts
Top