First, try to give your disaster planning some scope. There is never one answer for every scenario, you'll never be able to identify every threat or scenario, and you'll never be able to plan for everything. So start small, and create a list of what you consider the most likely threats: personal, local, regional, national, global.
Personal. This is the step most "preppers" skip over, because it's not nearly as glorious and planning for the end of the world. But what happens if you (or a spouse or dependent) loses a job, or gets sick or injured, or dies? Do you have your estate planning in order? Do you have sufficient life and disability insurance (your work probably doesn't provide enough) a will, health care proxy, power of attorney, etc? Do you have enough cash in the bank (or under the mattress, if you prefer) to get you through a rocky period? Remember, you can't pay the mortgage with canned goods or ammo, and a maxed out credit card is far more of a liability than the survival gear you bought with it is an asset.
Also consider, what happens if nothing goes wrong, ever? Are you investing properly in your retirement?
Next, local. There's a fire, flood, localized natural (or man-made) disaster. Is your insurance up to date? Do you have copies of vital documents in a safe place (preferably not in the home)? Do you have an evacuation plan? Do you have a bug out bag? And when you pack your bug out bag, consider what is really going to matter. In a local disaster (and most disasters are local) you'll have all the resources of the surrounding region at your disposal, but you can expect to lose most of the resources in your home. So if your house goes up in flames, what's going to be more important to have - important documents and family photo albums, or guns and camping gear?
Regional. This is where you really need to consider bug in vs. bug out. Bug out should be a worst case scenario, because you'll be walking away from the relative security of your home, and leaving the bulk of your resources. If you have to bug out, plan evacuation routes and bug out destinations ahead of time. If you're single (or have a partner who can ride) a motorcycle or dirt bike is probably an excellent bug out vehicle for your location.
However, keep in mind that even in the most epic disaster, there will still be a .gov presence, and you'll need to operate in tandem with them. You may be forced into certain evacuation routes, methods, or destinations. Plan with flexibility. Also plan with speed and decisiveness. If you decide to go, go. The people who get out first will be the ones who get out fastest and with the most options. The people who wait until the last minute will be the ones forced onto buses and into FEMA shelters.
National/global. Personally, if things get this bad, I know I'm f*cked, so I'll let others address these scenarios. Just know that unless you have a self sufficient and fully sustainable bug out location that's well off the grid, and the means to get to it, you're probably f*cked too. Most people don't have the means or commitment to prep for this, and frankly, I think the cost/benefit makes that okay, but that's a conversation for another thread.