Use a V-Max round in about any weight available, at close range (50 yds) you will most likely have a through & through, going in like a grape, and coming out like a grape fruit. Now the really light ones, like the 36 grain, and the 40 grain, probably would not exit. I have seen them used on coyotes where there was a tiny entrance hole, but the entire chest cavity was just a bunch of strawberry jelly.
even the full metal jacket boat tail is more than capable at close range, this is what the guys called "The Meat Ax" in the early days of the M-16 in Vietnam. The reason being, that upon impact the bullet would become destabilized, and would tumble. This would cause horrific wounds, the boys loved the black rifle, until it started jamming because the Ordinance Dept. changed the type of powder which resulted in excessive carbon buildup. They were also under the misconception that the "Futuristic" rifle did not require cleaning, so no cleaning kits were ever issued. This situation got a lot of boys killed over there, just another example of brainless Government Bureaucrats screwing things up.