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The Power of III
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1,365 Posts
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from Yahoo Finance
July 13, 2009

Link:
http://finance.yahoo.com/news/Inovio-Biomedical-H1N1-bw-2734850862.html?x=0&.v=1

Excerpt:

SAN DIEGO--(BUSINESS WIRE)--Inovio Biomedical Corporation (NYSE Amex:INO), a leader in DNA vaccine design, development and delivery, announced today that the company's SynCon™ H1N1 influenza DNA vaccines achieved protective antibody responses against H1N1 swine influenza virus (A/Swine/Iowa/35233/1999) in 100% of pigs immunized with a two-dose vaccine regimen.
Dr. J. Joseph Kim, Inovio’s CEO, said, “Our innovative SynCon™ technology has the potential to protect people from influenza strains not exactly like the ones that make up the existing vaccines. This is a clear advantage for our universal flu program over conventional influenza vaccines. We are pleased to report our H1N1 preclinical results using pigs, a more natural model for the current influenza pandemic. We look forward to advancing our SynCon™ universal flu vaccine program toward clinical investigation.”

Inovio’s novel SynCon™ technology enables the company to design DNA-based vaccines with the potential to protect against unmatched sub-types and strains of pathogens. Inovio has created SynCon™ DNA vaccines based on influenza HA, NA, and NP proteins that are common to strains H1N1, H2N2, H3N2, and H5N1, which make up the majority of seasonal and pandemic influenza. Using a designer approach, Inovio can formulate these DNA plasmids together to rapidly develop a universal influenza vaccine potentially targeting all these strains. The resulting vaccine could target seasonal as well as pandemic-potential influenza strains such as avian influenza and swine flu, which has already been designated pandemic status. Significantly, being based on a common set of antigens derived from a broad range of flu strains, such a universal vaccine would have the potential to provide greater protection against evolving, unmatched flu strains.
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homesteading mama.
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109 Posts
Wow, that's kind of amazing. If you read Inovio's description of SynCon(TM) technology, it sounds like pretty impressive technology, though replete with super-'sciencey' terms and phrases that mean nothing at all.

I'm a technophobe. These people are bringing us one step closer to some sort of genetic apocalypse. They claim that the vaccines can be programmed to essentially catch any mutations that may occur in a viral strand because it is the DNA itself to which your body becomes immune (EDIT: They mark specific genes so that your body initiates an immune response to separate components of the DNA, thus increasing the chances that it will still protect against a mutation).

Basically it's a synthetic virus that doesn't replicate.

Then they put it into your body using "electroporation."
this method uses electrical pulses to create pores in cells of muscle or skin and enhances intracellular delivery of DNA plasmids by 1,000 times or more.
http://www.inovio.com/technology/howelectroporationworks.htm
Sorry, this just blows my mind.
Thanks for posting! :thumb:
 
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